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Articles Published Processes
10/14/2022 12:54:50 PM | Browse: 362 | Download: 887
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Received |
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2022-05-19 02:25 |
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Peer-Review Started |
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2022-05-19 02:28 |
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To Make the First Decision |
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Return for Revision |
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2022-07-14 12:49 |
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Revised |
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2022-07-15 10:17 |
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Second Decision |
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2022-09-05 03:24 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-09-06 18:17 |
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Articles in Press |
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2022-09-06 18:17 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-09-28 14:44 |
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Publish the Manuscript Online |
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2022-10-14 12:54 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Go-Ichi-Ni-San 2: A potential biomarker and therapeutic target in human cancers
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Dan-Dan Shan, Qiu-Xian Zheng and Zhi Chen |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Science and Technology Major Project of China |
2018ZX10302-206 |
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| Corresponding Author |
Zhi Chen, MD, PhD, Professor, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, No. 79 Qingchun Road, Shangcheng District, Hangzhou 310003, Zhejiang Province, China. zjuchenzhi@zju.edu.cn |
| Key Words |
Go-Ichi-Ni-San; Go-Ichi-Ni-San 2; Cancer; Biomarker; Clinicopathological characteristics; Molecular mechanism |
| Core Tip |
The Go-Ichi-Ni-San (GINS) complex plays a crucial role in DNA replication and the cell cycle. The GINS complex consists of four subunits encoded by the GINS1, GINS2, GINS3, and GINS4 genes. This review explores the differential expression of GINS2 as a novel target in human cancers. GINS2 is upregulated in most tumors and can influence tumorigenesis and progression through competing endogenous RNA effects and signaling pathways. Therefore, GINS2 may become a new target for the diagnosis and treatment of many cancers. |
| Publish Date |
2022-10-14 12:54 |
| Citation |
Shan DD, Zheng QX, Chen Z. Go-Ichi-Ni-San 2: A potential biomarker and therapeutic target in human cancers. World J Gastrointest Oncol 2022; 14(10): 1892-1902 |
| URL |
https://www.wjgnet.com/1948-5204/full/v14/i10/1892.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v14.i10.1892 |
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