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Articles Published Processes
3/7/2023 4:31:44 PM | Browse: 259 | Download: 708
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Received |
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2022-09-13 10:19 |
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Peer-Review Started |
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2022-09-13 10:22 |
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To Make the First Decision |
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Return for Revision |
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2022-09-29 20:43 |
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Revised |
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2022-10-12 08:42 |
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Second Decision |
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2022-11-14 03:27 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-11-17 15:18 |
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Articles in Press |
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2022-11-17 15:18 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2023-02-20 13:15 |
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Typeset the Manuscript |
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2023-03-02 06:12 |
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Publish the Manuscript Online |
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2023-03-07 16:31 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Review |
| Article Title |
Molecular mechanisms targeting drug-resistance and metastasis in colorectal cancer: Updates and beyond
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Samar Al Bitar, Marwan El-Sabban, Samer Doughan and Wassim Abou-Kheir |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Wassim Abou-Kheir, MSc, PhD, Associate Professor, Department of Anatomy, Cell Biology and Physiological Sciences, American University of Beirut, Bliss St, Beirut 1107-2020, Lebanon. wa12@aub.edu.lb |
| Key Words |
Colorectal cancer; Metastatic colorectal cancer; Targeted therapy; Drug-resistance; Personalized medicine |
| Core Tip |
Efforts of cancer research has yielded significant advances in our understanding of the molecular mechanisms underlying colorectal cancer (CRC) resistance and metastasis. Therapeutic strategies centered on targeted molecules involved in CRC progression has been shown to be highly promising in overcoming resistance to conventional treatments. Targeted agents are currently being evaluated in preclinical and clinical studies to identify novel pharmacological targets and to study the efficacy of personalized medicine- based approaches. |
| Publish Date |
2023-03-07 16:31 |
| Citation |
Al Bitar S, El-Sabban M, Doughan S, Abou-Kheir W. Molecular mechanisms targeting drug-resistance and metastasis in colorectal cancer: Updates and beyond. World J Gastroenterol 2023; 29(9): 1395-1426 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i9/1395.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i9.1395 |
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