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Articles Published Processes
1/4/2023 5:53:01 AM | Browse: 295 | Download: 810
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Received |
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2022-10-04 09:21 |
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Peer-Review Started |
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2022-10-04 09:23 |
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To Make the First Decision |
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Return for Revision |
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2022-11-15 05:31 |
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Revised |
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2022-11-29 03:18 |
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Second Decision |
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2022-12-14 04:07 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-12-14 14:30 |
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Articles in Press |
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2022-12-14 14:30 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-12-22 23:33 |
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Publish the Manuscript Online |
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2023-01-04 05:53 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Emerging novel targets for nonalcoholic fatty liver disease treatment: Evidence from recent basic studies
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Guang-Yan Wang, Xiao-Yan Zhang, Chun-Jiong Wang and You-Fei Guan |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82170635 |
| National Natural Science Foundation of China |
81970606 |
| National Natural Science Foundation of China |
81822006 |
| Natural Science Foundation of Tianjin |
20JCYBJC01120 |
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| Corresponding Author |
You-Fei Guan, MD, Professor, Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Dalian Medical University, No. 9, West Section of Lushun South Road, Lushunkou District, Dalian 116044, Liaoning Province, China. guanyf@dmu.edu.cn |
| Key Words |
Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; Pharmaceutical strategies; Liver microenvironment; Gut-liver axis; Adipose tissue-liver axis |
| Core Tip |
Because of the urgent need to develop therapeutic approaches to treat nonalcoholic fatty liver disease (NAFLD), a large body of basic research has focused on the mechanisms of NAFLD to explore the possibility of new approaches to treat the disease. The current review summarizes studies reported in recent years that not only provide new insights into the mechanisms of NAFLD development but also explore the possibility of treating NAFLD by targeting newly identified signaling pathways. Evidence focusing on the intrahepatic targets involved in the pathogenesis of NAFLD as well as extrahepatic targets affecting liver metabolism and function are discussed. |
| Publish Date |
2023-01-04 05:53 |
| Citation |
Wang GY, Zhang XY, Wang CJ, Guan YF. Emerging novel targets for nonalcoholic fatty liver disease treatment: Evidence from recent basic studies. World J Gastroenterol 2023; 29(1): 75-95 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i1/75.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i1.75 |
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