| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Acoustic radiation force impulse predicts long-term outcomes in a large-scale cohort: High liver cancer, low comorbidity in hepatitis B virus
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Jennifer Tai, Adam P Harrison, Hui-Ming Chen, Chiu-Yi Hsu, Tse-Hwa Hsu, Cheng-Jen Chen, Wen-Juei Jeng, Ming-Ling Chang, Le Lu and Dar-In Tai |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Chang Gung Memorial Hospital and PAII Inc. |
SMRPG3I0011 |
|
| Corresponding Author |
Dar-In Tai, MD, PhD, Professor, Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, No. 5 FuXing Street, Guishan Dist, Taoyuan 33305, Taiwan. tai48978@cgmh.org.tw |
| Key Words |
Non-alcoholic fatty liver disease; Hepatitis B; Hepatocellular carcinoma; Acoustic radiation force impulse; Mortality; Comorbidity |
| Core Tip |
Among 1962 patients who received an acoustic radiation force impulse (ARFI) study, the 5-year risk of hepatocellular carcinoma (HCC) was 5.9% and 9.8% for those ARFI-graded with severe fibrosis and cirrhosis, respectively. The prevalence of HCC was highest in the hepatitis B virus (HBV) group. However, the HBV group showed the lowest comorbidities among the groups after adjusting for age, gender, and body mass index. This made the mortality rate similar among the groups. ARFI alone had an area under the receiver operating characteristic curve (AUROC) of 0.742 for prediction of HCC in 5 years. The AUROC increased to 0.828 after adding etiology, gender, age, and platelet score. Those patients with ARFI-estimated severe fibrosis or cirrhosis should receive active surveillance of HCC in all etiologies. |
| Publish Date |
2023-04-13 08:14 |
| Citation |
Tai J, Harrison AP, Chen HM, Hsu CY, Hsu TH, Chen CJ, Jeng WJ, Chang ML, Lu L, Tai DI. Acoustic radiation force impulse predicts long-term outcomes in a large-scale cohort: High liver cancer, low comorbidity in hepatitis B virus. World J Gastroenterol 2023; 29(14): 2188-2201 |
| URL |
https://www.wjgnet.com/1007-9327/full/v29/i14/2188.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v29.i14.2188 |
