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Articles Published Processes
5/19/2023 10:53:20 AM | Browse: 177 | Download: 498
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Received |
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2022-12-23 06:07 |
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Peer-Review Started |
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2022-12-23 06:14 |
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To Make the First Decision |
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Return for Revision |
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2023-03-01 01:00 |
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Revised |
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2023-03-09 17:00 |
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Second Decision |
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2023-03-24 03:03 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-03-29 19:02 |
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Articles in Press |
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2023-03-29 19:02 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2023-04-04 17:16 |
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Typeset the Manuscript |
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2023-05-16 07:16 |
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Publish the Manuscript Online |
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2023-05-19 10:53 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Minireviews |
| Article Title |
Deep brain stimulation for autism spectrum disorder
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Stefano Marini, Lucia D'Agostino, Carla Ciamarra and Alessandro Gentile |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Stefano Marini, MD, Doctor, Doctor, Department of Mental Health, National Health Service, Via del Molinello n. 1, Termoli 86039, Italy. sfnmarini@gmail.com |
| Key Words |
Deep brain stimulation; Autism spectrum disorder; Comorbidities; Drug resistant; New therapeutic perspectives |
| Core Tip |
Deep brain stimulation (DBS) is a medical treatment that aims at obtaining therapeutic effects by applying chronic electrical impulses in specific brain structures and neurological circuits. Autism spectrum disorder comprises a group of developmental disabilities that are often associated with numerous medical and psychiatric comorbidities that worsen the quality of life of patients and their caregivers. Comorbidities often require multiple drug treatments with an increasing rate of treatment resistance. Thirteen studies have been considered in this paper. Up to date, DBS has been used for the stimulation of the nucleus accumbens, globus pallidus internus, anterior limb of the internal capsule, ventral anterior limb of the internal capsule, basolateral amygdala, ventral capsule and ventral striatum, medial forebrain bundle, and posterior hypothalamus. In the total sample of 16 patients, 4 were adolescents (all males), and 12 were adults (5 males and 7 females). All patients had symptoms resistant to multiple drug therapy. Only one patient was considered not a responder to DBS. Among the new therapeutic perspectives, as evidenced by the studies presented in this article, DBS could be a valid option. However, further, and more in-depth research is needed in this field. |
| Publish Date |
2023-05-19 10:53 |
| Citation |
<p>Marini S, D'Agostino L, Ciamarra C, Gentile A. Deep brain stimulation for autism spectrum disorder. <i>World J Psychiatry</i> 2024; In press</p> |
| URL |
https://www.wjgnet.com/2220-3206/full/v13/i5/174.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v13.i5.174 |
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