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Articles Published Processes
10/24/2014 5:02:00 PM | Browse: 1088 | Download: 1081
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Received |
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2013-12-22 14:15 |
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Peer-Review Started |
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2013-12-22 19:48 |
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To Make the First Decision |
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2014-02-13 16:26 |
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Return for Revision |
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2014-02-20 22:33 |
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Revised |
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2014-03-16 17:53 |
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Second Decision |
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2014-06-27 17:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-06-27 17:50 |
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Articles in Press |
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2014-06-27 18:10 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-10-22 17:08 |
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Publish the Manuscript Online |
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2014-10-24 17:01 |
Category |
Orthopedics |
Manuscript Type |
Autobiography |
Article Title |
Intra-articular transplantation of porcine adipose-derived stem cells for the treatment of canine osteoarthritis: A pilot study
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Manuscript Source |
Invited Manuscript |
All Author List |
Intra-articular transplantation of porcine adipose-derived stem cells for the treatment of canine osteoarthritis: A pilot study |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Taiwan University |
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Corresponding Author |
Dr. Ching-Shwun Lin, Department of Urology, School of Medicine, University of California, 533 Parnassus Ave, San Francisco, CA 94143-0738,
United States. clin@urology.ucsf.edu
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Key Words |
Canine osteoarthritis; Adipose-derived stem cells; Intra-articular transplantation; Intra-articular injection; Veterinary clinical study |
Core Tip |
Intra-articular injection of autologous adipose-derived stem cells (ADSCs) has been shown to be effective in treating osteoarthritis in dogs. However, most veterinary clinics lack the equipment and expertise for ADSC isolation. The present study showed that intra-articular injection of porcine ADSCs into the diseased stifle joint of three dogs improved their mobility and activity and lessened their pain. The injection of porcine ADSCs elicited no signs of inflammation or immunological reaction. Thus, porcine ADSCs can substitute for autologous canine ADSCs, and such a treatment strategy can drastically reduce treatment cost.
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Publish Date |
2014-10-24 17:01 |
Citation |
Tsai SY, Huang YC, Chueh LL, Yeh LS, Lin CS. Intra-articular transplantation of porcine adipose-derived stem cells for the treatment of canine osteoarthritis: A pilot study. World J Transplant 2014; 4(3): 196-205 |
URL |
http://www.wjgnet.com/2220-3230/full/v4/i3/196.htm |
DOI |
http://dx.doi.org/10.5500/wjt.v4.i3.196 |
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