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Articles Published Processes
11/15/2023 1:46:53 PM | Browse: 212 | Download: 658
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Received |
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2023-06-27 06:09 |
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Peer-Review Started |
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2023-06-27 06:12 |
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To Make the First Decision |
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Return for Revision |
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2023-08-26 13:16 |
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Revised |
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2023-09-06 09:17 |
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Second Decision |
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2023-10-19 02:00 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-10-23 06:57 |
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Articles in Press |
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2023-10-23 06:57 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-11-03 08:12 |
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Publish the Manuscript Online |
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2023-11-15 13:46 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Glutamine addiction and therapeutic strategies in pancreatic cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Lin-Lin Ren, Tao Mao, Pin Meng, Li Zhang, Hong-Yun Wei and Zi-Bin Tian |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China (General Program) |
82273393 |
| National Natural Science Foundation of China (General Program) |
81602056 |
| Natural Science Foundation of Shandong Province |
ZR2016HQ45 |
| Natural Science Foundation of Shandong Province |
ZR2020LZL004 |
| Shandong Traditional Chinese Medicine Science and Technology Project |
2021M161 |
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| Corresponding Author |
Tao Mao, Doctor, MD, PhD, Associate Chief Physician, Doctor, Doctor, Teacher, Department of Gastroenterology, The Affiliated Hospital of Qingdao University, No. 16 Jiangsu Road, Qingdao 266000, Shandong Province, China. maotao@qdu.edu.cn |
| Key Words |
Pancreatic cancer; Glutamine metabolism; Cancer treatment; Therapeutic strategies |
| Core Tip |
Most pancreatic ductal adenocarcinomas (PDAC) are diagnosed at an advanced stage, missing the opportunity for surgical treatment and responding poorly to radiotherapy and targeted therapies. Glutamine is a non-essential amino acid that is found in high levels in normal humans. Glutamine metabolism could provide raw material for the synthesis of important molecules and meet the needs of rapid growth and proliferation of tumor cells. The study of glutamine metabolic pathways targeting PDAC may provide new strategies for pancreatic cancer treatment. |
| Publish Date |
2023-11-15 13:46 |
| Citation |
Ren LL, Mao T, Meng P, Zhang L, Wei HY, Tian ZB. Glutamine addiction and therapeutic strategies in pancreatic cancer. World J Gastrointest Oncol 2023; 15(11): 1852-1863 |
| URL |
https://www.wjgnet.com/1948-5204/full/v15/i11/1852.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v15.i11.1852 |
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