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Articles Published Processes
7/12/2023 7:57:45 AM | Browse: 265 | Download: 1042
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Received |
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2023-04-27 16:01 |
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Peer-Review Started |
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2023-04-27 16:04 |
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To Make the First Decision |
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Return for Revision |
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2023-05-08 03:32 |
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Revised |
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2023-05-19 12:40 |
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Second Decision |
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2023-06-26 02:56 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-06-26 07:17 |
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Articles in Press |
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2023-06-26 07:17 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-07-05 02:01 |
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Publish the Manuscript Online |
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2023-07-12 07:57 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Genetics & Heredity |
| Manuscript Type |
Case Report |
| Article Title |
Antithrombin III deficiency in a patient with recurrent venous thromboembolism: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jia-Qing Luo, Shuai-Shuai Mao, Jin-Yi Chen, Xue-Ying Ke, Yue-Feng Zhu, Wei Huang, Hai-Ming Sun and Zhen-Jie Liu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the National Natural Science Foundation of China |
81670433 and 81970398 |
| the Project of Zhejiang Medical Young Talents (2017) |
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| Zhejiang Medical and Health Science and Technology Project |
2020RC014 |
| the Natural Science Foundation of Zhejiang Province |
LR22H020002 |
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| Corresponding Author |
Hai-Ming Sun, MD, Chief Physician, Department of Vascular Surgery, Changxing People's Hospital, No. 66 Taihu Middle Road, Changxing 313100, Zhejiang Province, China. sun76543212023@163.com |
| Key Words |
Case report; Anticoagulant therapy; Single nucleotide variant; SERPINC1; Venous thrombosis; Antithrombin |
| Core Tip |
Hereditary thrombophilia can be attributed to mutations in genes such as PROS, PROC, SERPINC1, and F5. Compared to mutations in other genes, mutations of SERPINC1 consistently lead to a more pronounced thrombophilia. Patients with this type of mutation are often advised to take warfarin as a therapeutic measure. However, evidence on the efficacy of direct oral anticoagulants is inadequate. Following identification of the SERPINC1 mutation, our patient was advised to take Rivaroxaban for 5 years to prevent the possibility of thrombus recurrence. This report may supply proof of the efficacy of direct oral anticoagulants in individuals suffering from hereditary thrombophilia. |
| Publish Date |
2023-07-12 07:57 |
| Citation |
Luo JQ, Mao SS, Chen JY, Ke XY, Zhu YF, Huang W, Sun HM, Liu ZJ. Antithrombin III deficiency in a patient with recurrent venous thromboembolism: A case report. World J Clin Cases 2023; 11(20): 4956-4960 |
| URL |
https://www.wjgnet.com/2307-8960/full/v11/i20/4956.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v11.i20.4956 |
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