Publication Name	World Journal of Hepatology
Manuscript ID	87798
Country	China

Received	2023-08-28 02:52
Peer-Review Started	2023-08-28 02:55
To Make the First Decision
Return for Revision	2023-11-22 07:07
Revised	2023-12-04 10:42
Second Decision	2023-12-18 03:52
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-01-09 11:54
Articles in Press	2024-01-09 11:54
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-02-05 00:15
Publish the Manuscript Online	2024-02-27 11:58

ISSN	1948-5182 (online)
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Category	Infectious Diseases
Manuscript Type	Minireviews
Article Title	Dynamic changes and clinical value of lipocalin 2 in liver diseases caused by microbial infections
Manuscript Source	Unsolicited Manuscript
All Author List	Feng Chen, Shan-Shan Wu, Chao Chen and Cheng Zhou
ORCID	Author(s) ORCID Number Cheng Zhou http://orcid.org/0000-0001-6502-5442
Funding Agency and Grant Number
Corresponding Author	Cheng Zhou, MD, Associate Professor, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, National Medical Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, No. 79 Qingchun Road, Hangzhou 310003, Zhejiang Province, China. zhoucheng0113@zju.edu.cn
Key Words	Lipocalin 2; Microbial infection; Immunity; Liver diseases
Core Tip	LCN2 is a sensitive marker for infections because its change can be detected at the very early stage of various pathogenic microorganism infections. Infection with a variety of pathogens can cause liver damage, and it is well established that LCN2 is expressed differently in different clinical conditions. By observing the level of LCN2, doctors can evaluate the progression of the disease and the treatment efficacy. LCN2 is also a predictor marker in some end-stage liver diseases and is promising as a new diagnostic marker. Due to its strong binding with iron, targeting LCN2 also shows great potential in the treatment of infectious diseases.
Publish Date	2024-02-27 11:58
Citation	Chen F, Wu SS, Chen C, Zhou C. Dynamic changes and clinical value of lipocalin 2 in liver diseases caused by micobial infections. World J Hepatol 2024; 16(2): 177-185
URL	https://www.wjgnet.com/1948-5182/full/v16/i2/177.htm
DOI	https://dx.doi.org/10.4254/wjh.v16.i2.177

Full Article (PDF)	WJH-16-177-with-cover.pdf
Full Article (Word)	WJH-16-177.docx
Manuscript File	87798_Auto_Edited-LJH-YJP.docx
Answering Reviewers	87798-Answering reviewers.pdf
Audio Core Tip	87798-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	87798-Conflict-of-interest statement.pdf
Copyright License Agreement	87798-Copyright license agreement.pdf
Peer-review Report	87798-Peer-review(s).pdf
Journal Editor-in-Chief Review Report	87798-Journal editor-in-chief review report.pdf
Scientific Misconduct Check	87798-Bing-Liu JH-2.png
Scientific Misconduct Check	87798-CrossCheck.png
Scientific Editor Work List	87798-Scientific editor work list.pdf