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10/1/2014 8:25:00 PM | Browse: 864 | Download: 594
Publication Name World Journal of Gastroenterology
Manuscript ID 8841
Country/Territory Italy
Received
2014-01-09 09:56
Peer-Review Started
2014-01-11 17:24
To Make the First Decision
2014-01-24 11:15
Return for Revision
2014-01-26 17:51
Revised
2014-02-18 22:19
Second Decision
2014-05-14 09:21
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-05-14 09:33
Articles in Press
2014-05-23 10:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-07-19 17:30
Typeset the Manuscript
2014-09-14 16:04
Publish the Manuscript Online
2014-10-01 20:25
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title IL28B polymorphism genotyping as predictor of rapid virologic response during interferon plus ribavirin treatment in hepatitis C virus genotype 1 patients
Manuscript Source Invited Manuscript
All Author List Chiara Rosso, Maria Lorena Abate, Alessia Ciancio, Silvia Strona, Gian Paolo Caviglia, Antonella Olivero, Giovanni Antonio Touscoz, Mario Rizzetto, Rinaldo Pellicano and Antonina Smedile
Funding Agency and Grant Number
Funding Agency Grant Number
Department of Medical Science, University of Turin
Corresponding Author Rinaldo Pellicano, MD, Department of Gastroenterology and Hepatology, Molinette Hospital, Via Cavour 31, 10126 Turin, Italy. rinaldo_pellican@hotmail.com
Key Words Hepatitis C virus-G1; Interleukin-28B rs12979860; Interleukin-28B rs8099917; Interferon sensitivity; Triple therapy
Core Tip This work provides more insights into the advantage of interleukin-28B rs12979860 and rs8099917 genotyping for therapy management in hepatitis C virus-G1 infected patients. The relevance of this approach is cost-effective at the time of decisions regarding triple therapy. We observed that in rs12979860 heterozygous patients, carriage of the rs8099917 G allele correlated with lack of viremia decrease early during treatment, when it is critical to assess for interferon sensitivity.
Publish Date 2014-10-01 20:25
Citation Rosso C, Abate ML, Ciancio A, Strona S, Caviglia GP, Olivero A, Touscoz GA, Rizzetto M, Pellicano R, Smedile A. IL28B polymorphism genotyping as predictor of rapid virologic response during interferon plus ribavirin treatment in hepatitis C virus genotype 1 patients. World J Gastroenterol 2014; 20(36): 13146-13152
URL http://www.wjgnet.com/1007-9327/full/v20/i36/13146.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i36.13146
Full Article (PDF) WJG-20-13146.pdf
Full Article (Word) WJG-20-13146.doc
Manuscript File 8841-Review.doc
Answering Reviewers 8841-Answering reviewers.pdf
Biostatistics Review Certificate Biostatistician_Review_Report_20140108171411.doc
Copyright License Agreement 8841-Copyright assignment.pdf
Peer-review Report 8841-Peer reviews.pdf
Scientific Editor Work List 8841-Scientific editor work list.pdf