Publication Name	World Journal of Gastroenterology
Manuscript ID	8841
Country	Italy

Received	2014-01-09 09:56
Peer-Review Started	2014-01-11 17:24
To Make the First Decision	2014-01-24 11:15
Return for Revision	2014-01-26 17:51
Revised	2014-02-18 22:19
Second Decision	2014-05-14 09:21
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-05-14 09:33
Articles in Press	2014-05-23 10:24
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-07-19 17:30
Typeset the Manuscript	2014-09-14 16:04
Publish the Manuscript Online	2014-10-01 20:25

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	IL28B polymorphism genotyping as predictor of rapid virologic response during interferon plus ribavirin treatment in hepatitis C virus genotype 1 patients
Manuscript Source	Invited Manuscript
All Author List	Chiara Rosso, Maria Lorena Abate, Alessia Ciancio, Silvia Strona, Gian Paolo Caviglia, Antonella Olivero, Giovanni Antonio Touscoz, Mario Rizzetto, Rinaldo Pellicano and Antonina Smedile
Funding Agency and Grant Number	Funding Agency Grant Number Department of Medical Science, University of Turin
Corresponding Author	Rinaldo Pellicano, MD, Department of Gastroenterology and Hepatology, Molinette Hospital, Via Cavour 31, 10126 Turin, Italy. rinaldo_pellican@hotmail.com
Key Words	Hepatitis C virus-G1; Interleukin-28B rs12979860; Interleukin-28B rs8099917; Interferon sensitivity; Triple therapy
Core Tip	This work provides more insights into the advantage of interleukin-28B rs12979860 and rs8099917 genotyping for therapy management in hepatitis C virus-G1 infected patients. The relevance of this approach is cost-effective at the time of decisions regarding triple therapy. We observed that in rs12979860 heterozygous patients, carriage of the rs8099917 G allele correlated with lack of viremia decrease early during treatment, when it is critical to assess for interferon sensitivity.
Publish Date	2014-10-01 20:25
Citation	Rosso C, Abate ML, Ciancio A, Strona S, Caviglia GP, Olivero A, Touscoz GA, Rizzetto M, Pellicano R, Smedile A. IL28B polymorphism genotyping as predictor of rapid virologic response during interferon plus ribavirin treatment in hepatitis C virus genotype 1 patients. World J Gastroenterol 2014; 20(36): 13146-13152
URL	http://www.wjgnet.com/1007-9327/full/v20/i36/13146.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i36.13146

Full Article (PDF)	WJG-20-13146.pdf
Full Article (Word)	WJG-20-13146.doc
Manuscript File	8841-Review.doc
Answering Reviewers	8841-Answering reviewers.pdf
Biostatistics Review Certificate	Biostatistician_Review_Report_20140108171411.doc
Copyright License Agreement	8841-Copyright assignment.pdf
Peer-review Report	8841-Peer reviews.pdf
Scientific Editor Work List	8841-Scientific editor work list.pdf