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Articles Published Processes
12/25/2023 11:08:58 AM | Browse: 164 | Download: 494
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Received |
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2023-09-25 16:25 |
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Peer-Review Started |
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2023-09-25 16:28 |
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To Make the First Decision |
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Return for Revision |
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2023-11-09 04:04 |
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Revised |
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2023-11-12 00:00 |
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Second Decision |
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2023-11-21 01:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2023-11-28 08:37 |
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Articles in Press |
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2023-11-28 08:37 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2023-12-21 03:02 |
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Publish the Manuscript Online |
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2023-12-25 11:08 |
| ISSN |
1949-8462 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2023. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Editorial |
| Article Title |
Inherited arrhythmias and gene therapy: Are there any ethical considerations to take into account?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Michael Spartalis, Eleftherios Spartalis and Gerasimos Siasos |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Michael Spartalis, Doctor, FACC, FESC, MS, MSc, PhD, Doctor, Doctor, 3rd Department of Cardiology, National and Kapodistrian University of Athens, 152 Mesogeion Ave, Athens 11527, Greece. msparta@med.uoa.gr |
| Key Words |
Arrhythmia; Sudden cardiac death; Genome editing; Long QT; Channelopathies; Mutation |
| Core Tip |
The use of genome editing to treat rhythm disturbances at the substrate level could provide a revolutionary treatment for disorders that the current standard of care is inadequate. Our knowledge of the disease is the only limit in identifying a perfect genome editing tool for several rhythm disturbances. As our understanding of gene vectors and transfer techniques progress, a novel therapy approach will be upon us, where cardiac muscles are altered to be impervious to rhythm disturbances, enhancing patients’ quality of living and relieving the burden on healthcare organizations. Ethical issues will eventually arise, as the treatments will be expensive. |
| Publish Date |
2023-12-25 11:08 |
| Citation |
Spartalis M, Spartalis E, Siasos G. Inherited arrhythmias and gene therapy: Are there any ethical considerations to take into account? World J Cardiol 2023; 15(12): 623-626 |
| URL |
https://www.wjgnet.com/1949-8462/full/v15/i12/623.htm |
| DOI |
https://dx.doi.org/10.4330/wjc.v15.i12.623 |
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