Publication Name	World Journal of Orthopedics
Manuscript ID	90261
Country	Japan

Received	2023-12-03 04:27
Peer-Review Started	2023-12-03 04:27
To Make the First Decision
Return for Revision	2023-12-28 00:48
Revised	2024-01-06 05:52
Second Decision	2024-01-24 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-01-24 07:55
Articles in Press	2024-01-24 07:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-03-08 00:22
Publish the Manuscript Online	2024-03-15 08:33

ISSN	2218-5836 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
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Category	Orthopedics
Manuscript Type	Case Report
Article Title	New method of local adjuvant therapy with bicarbonate Ringer’s solution for tumoral calcinosis: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Takashi Noguchi, Akio Sakamoto, Kensaku Kakehi and Shuichi Matsuda
ORCID	Author(s) ORCID Number Takashi Noguchi http://orcid.org/0000-0003-2965-4772 Akio Sakamoto http://orcid.org/0000-0002-7518-1606 Shuichi Matsuda http://orcid.org/0000-0003-0802-1255
Funding Agency and Grant Number
Corresponding Author	Akio Sakamoto, MD, PhD, Associate Professor, Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Shogoin, Kawahara-cho 54, Sakyo-ku, Kyoto 606-8507, Japan. akiosaka@kuhp.kyoto-u.ac.jp
Key Words	Tumoral calcinosis; Adjuvant therapy; Bicarbonate; Ringer’s solution; Surgery; Case report
Core Tip	Tumoral calcinosis, which occurs in 2%-3% of hemodialysis patients, involves calcium phosphate deposits, thus making surgical resection challenging. Hydroxyapatite, the main component of tumoral calcinosis, infiltrates tissues extensively. A bicarbonate Ringer’s solution is used post-resection. A 49-year-old hemodialysis patient with calcified shoulder, hip, and foot lesions underwent the bicarbonate dissolution method. After resection, the operative field was washed with the solution. This simple and effective treatment offers a novel approach for managing tumoral calcinosis in hemodialysis patients.
Publish Date	2024-03-15 08:33
Citation	Noguchi T, Sakamoto A, Kakehi K, Matsuda S. New method of local adjuvant therapy with bicarbonate Ringer’s solution for tumoral calcinosis: A case report. World J Orthop 2024; 15(3): 302-309
URL	https://www.wjgnet.com/2218-5836/full/v15/i3/302.htm
DOI	https://dx.doi.org/10.5312/wjo.v15.i3.302

Full Article (PDF)	WJO-15-302-with-cover.pdf
CARE Checklist–2016	90261-CARE Checklist (2016).pdf
Manuscript File	90261_Auto_Edited-YJP.docx
Answering Reviewers	90261-Answering reviewers.pdf
Audio Core Tip	90261-Audio core tip.mp4
Conflict-of-Interest Disclosure Form	90261-Conflict-of-interest statement.pdf
Copyright License Agreement	90261-Copyright license agreement.pdf
Signed Consent for Treatment Form(s) or Document(s)	90261-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	90261-Language certificate.pdf
Peer-review Report	90261-Peer-review(s).pdf
Scientific Editor Work List	90261-Scientific editor work list.pdf
CrossCheck Report	90261-CrossCheck report.pdf