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Articles Published Processes
9/12/2014 8:41:00 PM | Browse: 7448 | Download: 1505
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2013-02-25 09:06 |
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Peer-Review Started |
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2013-02-26 09:00 |
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First Decision by Editorial Office Director |
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2013-03-19 14:29 |
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Second Decision by Editor |
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2013-05-18 16:58 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2013-05-19 23:55 |
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Articles in Press |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-08-23 17:21 |
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Publish the Manuscript Online |
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2013-09-14 11:17 |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Autobiography |
| Article Title |
5-ASA colonic mucosal concentrations resulting from different pharmaceutical formulations in ulcerative colitis
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Renata D’Incà, Martina Paccagnella, Romilda Cardin, Surajit Pathak, Vincenzo Baldo, Maria Cecilia Giron and Giacomo Carlo Sturniolo |
| Funding Agency and Grant Number |
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| Corresponding Author |
Dr. Renata D’Incà, Division of Gastroenterology, Department of Surgical, Oncological and Gastroenterological Sciences, VI piano Monoblocco, Via Giustiniani 2, 35127 Padova, Italy. dinca@unipd.it |
| Key Words |
Mucosal concentration; Inflammatory bowel diseases; 5-aminosalicylic acid |
| Core Tip |
We report on the concentrations of 5-aminosalicylic acid in the colonic mucosa of ulcerative colitis patients. Significant variations in concentration were observed that were dependent on the type of pharmaceutical formulation and the presence of active disease. Combined oral and topical therapy yielded higher tissue mesalamine concentrations. These differences should be taken into account in treatment strategies, especially in view of the fact that mesalamine can induce mucosal healing in ulcerative colitis. |
| Publish Date |
2013-09-14 11:17 |
| Citation |
D’Incà R, Paccagnella M, Cardin R, Pathak S, Baldo V, Giron MC, Sturniolo GC. 5-ASA colonic mucosal concentrations resulting from different pharmaceutical formulations in ulcerative colitis. World J Gastroenterol 2013; 19(34): 5665-5670 |
| URL |
http://www.wjgnet.com/1007-9327/full/v19/i34/5665.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v19.i34.5665 |
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