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9/12/2014 8:41:00 PM | Browse: 6739 | Download: 543
Publication Name World Journal of Gastroenterology
Manuscript ID 2475
Country of Manuscript Source Italy
Received
2013-02-25 09:06
Peer-Review Started
2013-02-26 09:00
To Make the First Decision
2013-03-18 15:34
Return for Revision
2013-03-19 14:29
Revised
Second Decision
2013-05-18 16:58
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-05-19 23:55
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2013-08-23 17:21
Publish the Manuscript Online
2013-09-14 11:17
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript type Autobiography
Article Title 5-ASA colonic mucosal concentrations resulting from different pharmaceutical formulations in ulcerative colitis
Manuscript Source Invited Manuscript
All Author List Renata D’Incà, Martina Paccagnella, Romilda Cardin, Surajit Pathak, Vincenzo Baldo, Maria Cecilia Giron and Giacomo Carlo Sturniolo
Funding Agency and Grant Number
Correspondence To Dr. Renata D’Incà, Division of Gastroenterology, Department of Surgical, Oncological and Gastroenterological Sciences, VI piano Monoblocco, Via Giustiniani 2, 35127 Padova, Italy. dinca@unipd.it
Keywords 5-aminosalicylic acid; Inflammatory bowel diseases; Mucosal concentration
Core Tip We report on the concentrations of 5-aminosalicylic acid in the colonic mucosa of ulcerative colitis patients. Significant variations in concentration were observed that were dependent on the type of pharmaceutical formulation and the presence of active disease. Combined oral and topical therapy yielded higher tissue mesalamine concentrations. These differences should be taken into account in treatment strategies, especially in view of the fact that mesalamine can induce mucosal healing in ulcerative colitis.
Publish Date 2013-09-14 11:17
Citation D’Incà R, Paccagnella M, Cardin R, Pathak S, Baldo V, Giron MC, Sturniolo GC. 5-ASA colonic mucosal concentrations resulting from different pharmaceutical formulations in ulcerative colitis. World J Gastroenterol 2013; 19(34): 5665-5670
Url http://www.wjgnet.com/1007-9327/full/v19/i34/5665.htm
DOI http://dx.doi.org/10.3748/wjg.v19.i34.5665
Full Article (PDF) WJG-19-5665.pdf
Manuscript File 2475-Review.docx
Answering Reviewers 2475-Answering reviewers.docx
Copyright License Agreement 2475-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 2475-Language certificate.pdf
Peer-review Report 2475-Peer review(s).pdf
Scientific Editor Work List 2475-Scientific editor work list.doc