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1/7/2019 10:39:41 AM | Browse: 59 | Download: 73
Publication Name World Journal of Gastroenterology
Manuscript ID 42847
Country of Manuscript Source China
Received
2018-10-17 02:40
Peer-Review Started
2018-10-17 07:26
To Make the First Decision
2018-11-22 06:24
Return for Revision
2018-11-22 07:23
Revised
2018-12-16 16:29
Second Decision
2018-12-19 09:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-12-20 01:46
Articles in Press
2018-12-20 01:46
Publication Fee Transferred
Edit the Manuscript by Language Editor
2018-12-24 04:04
Typeset the Manuscript
2019-01-06 10:19
Publish the Manuscript Online
2019-01-07 10:39
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Specialty Gastroenterology and Hepatology
Manuscript type Retrospective Study
Article Title Nomograms for predicting pathological response to neoadjuvant treatments in patients with rectal cancer
Manuscript Source Invited Manuscript
All Author List Dong-Lin Ren, Juan Li, Hui-Chuan Yu, Shao-Yong Peng, Wei-Da Lin, Xiao-Lin Wang, Roshan Ara Ghoorun and Yan-Xin Luo
ORCID
Author(s) ORCID Number
Dong-Lin Ren http://orcid.org/0000-0001-5599-8654
Juan Li http://orcid.org/0000-0002-0536-3236
Hui-Chuan Yu http://orcid.org/0000-0001-8357-1615
Shao-Yong Peng http://orcid.org/0000-0002-5489-4869
Wei-Da Lin http://orcid.org/0000-0002-8225-0032
Xiao-Lin Wang http://orcid.org/0000-0001-6970-3992
Roshan Ara Ghoorun http://orcid.org/0000-0002-9776-4722
Yan-Xin Luo http://orcid.org/0000-0002-5200-3997
Funding Agency and Grant Number
Funding Agency Grant Number
National Basic Research Program of China (973 Program) 2015CB554001
National Natural Science Foundation of China 81472257 81502022
Natural Science Fund for Distinguished Young Scholars of Guangdong Province 2016A030306002
Tip-top Scientific and Technical Innovative Youth Talents of Guangdong special support program 2015TQ01R454
Natural Science Foundation of Guangdong Province 2016A030310222 2017A030313580
Science and Technology Program of Guangzhou 201506010099 2014Y2-00160
Fundamental Research Funds for the Central Universities (Sun Yat-sen University) 2015ykzd10 16ykpy35 17ykpy67
National Key Clinical Discipline
Correspondence To Yan-Xin Luo, MD, PhD, Associate Professor, Chief Doctor, Surgical Oncologist, Department of Colon and Rectum Surgery, Guangdong Institute of Gastroenterology, Guangdong Provincial Key Laboratory of Colorectal and Pelvic Floor Diseases, The Sixth Affiliated Hospital, Sun Yat-sen University, 26 Yuancun Erheng Road, Tianhe District, Guangzhou 510655, Guangdong Province, China. luoyx25@mail.sysu.edu.cn
Keywords Neoadjuvant therapy; Locally advanced rectal cancer; Nomogram; Prediction of pathological response; Complete pathological response; Good downstaging
Core Tip In this study, we established accurate nomograms for predicting the pathological response (PR) to preoperative neoadjuvant therapy (NT) regimens based on pretreatment parameters for locally advanced rectal cancer (LARC) patients. Logistic regression and nomograms were developed to predict the probability of complete pathological response and good downstaging, respectively, for all patients and for subgroups based on NT regimens. In conclusion, nomograms have been established for predicting the PR to different NT regimens for LARC patients; and these nomograms can be used to facilitate developing individualized treatments.
Publish Date 2019-01-07 10:39
Citation Ren DL, Li J, Yu HC, Peng SY, Lin WD, Wang XL, Ghoorun RA, Luo YX. Nomograms for predicting pathological response to neoadjuvant treatments in patients with rectal cancer. World J Gastroenterol 2019; 25(1): 118-137
Url https://www.wjgnet.com/1007-9327/full/v25/i1/118.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i1.118
Full Article (PDF) WJG-25-118.pdf
Full Article (Word) WJG-25-118.docx
Manuscript File 42847-Review.docx
Answering Reviewers 42847-Answering reviewers.pdf
Audio Core Tip 42847-Audio core tip.mp3
Biostatistics Review Certificate 42847-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 42847-Conflict-of-interest statement.pdf
Copyright License Agreement 42847-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 42847-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 42847-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 42847-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 42847-Language certificate.pdf
Supplementary Material 42847-Supplementary-Material-revision.docx
Peer-review Report 42847-Peer-review(s).pdf
Scientific Misconduct Check 42847-Scientific misconduct check.pdf
Scientific Editor Work List 42847-Scientific editor work list.pdf