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1/11/2020 12:25:00 AM | Browse: 124 | Download: 104
Publication Name World Journal of Experimental Medicine
Manuscript ID 48476
Country/Territory Brazil
Received
2019-05-06 00:38
Peer-Review Started
2019-05-08 00:43
To Make the First Decision
2019-09-09 08:37
Return for Revision
2019-09-10 08:20
Revised
2019-11-26 18:56
Second Decision
2019-12-11 08:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-12-15 05:00
Articles in Press
2019-12-15 05:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-01-03 07:36
Publish the Manuscript Online
2020-01-11 00:25
ISSN 2220-315x (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, Research and Experimental
Manuscript Type Basic Study
Article Title Alendronate disturbs femoral growth due to changes during immunolocalization of transforming growth factor-β1 and bone morphogenetic protein-2 in epiphyseal plate
Manuscript Source Unsolicited Manuscript
All Author List Juliana Souza Vieira, Emanuelle Juliana Cunha, Juliana Feltrin de Souza, Luis Henrique Koeler Chaves, Jessica Lakes de Souza and Allan Fernando Giovanini
ORCID
Author(s) ORCID Number
Juliana Souza Vieira http://orcid.org/0000-0001-6297-5784
Emanuelle Juliana Cunha http://orcid.org/0000-0002-6780-7904
Juliana Feltrin de Souza http://orcid.org/0000-0001-9969-3721
Luis Henrique Koeler Chaves http://orcid.org/0000-0002-8463-7361
Jessica Lakes de Souza http://orcid.org/0000-0003-2840-5811
Allan Fernando Giovanini http://orcid.org/0000-0002-1637-2955
Funding Agency and Grant Number
Corresponding author Allan Fernando Giovanini, PhD, Associate Professor, Dentistry, Positivo University, R. Prof. Pedro Viriato Parigot de Souza, 5300, Campo Comprido, Curitiba 81280-330, Brazil. afgiovanini@gmail.com
Keywords Alendronate; Bone development; Epiphyseal plate; Bone morphogentic protein-2; Transforming growth factor-β1;
Core Tip This is the first study that addresses the likely action of alendronate in appendicular bone development. Through of macroscopic, immunohistochemical and histological analysis, we revealed that alendronatemay impairs the bone growth, since alters the usual development of epiphyseal plate associated to changes in the immunolocalization of transforming growth factor-β1 and bone morphogenetic protein-2.
Publish Date 2020-01-11 00:25
Citation Vieira JS, Cunha EJ, de Souza JF, Chaves LHK, de Souza JL, Giovanini AF. Alendronate disturbs femoral growth due to changes during immunolocalization of transforming growth factor-β1 and bone morphogenetic protein-2 in epiphyseal plate. World J Exp Med 2020; 10(1): 1-9
Url https://www.wjgnet.com/2220-315x/full/v10/i1/1.htm
DOI https://dx.doi.org/10.5493/wjem.v10.i1.1
Full Article (PDF) WJEM-10-1.pdf
Full Article (Word) WJEM-10-1.docx
Manuscript File 48476-Review.docx
Answering Reviewers 48476-Answering reviewers.pdf
Audio Core Tip 48476-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 48476-Conflict-of-interest statement.pdf
Copyright License Agreement 48476-Copyright license agreement.pdf
Institutional Animal Care and Use Committee Approval Form or Document 48476-Institutional animal care and use committee statement.pdf
Non-Native Speakers of English Editing Certificate 48476-Language certificate.pdf
Peer-review Report 48476-Peer-review(s).pdf
Scientific Misconduct Check 48476-Scientific misconduct check.pdf
Scientific Editor Work List 48476-Scientific editor work list.pdf