BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
5/14/2020 3:43:04 AM | Browse: 778 | Download: 1268
Publication Name World Journal of Gastroenterology
Manuscript ID 54433
Country/Territory Germany
Received
2020-02-04 11:46
Peer-Review Started
2020-02-04 11:46
To Make the First Decision
Return for Revision
2020-03-21 23:09
Revised
2020-04-03 09:07
Second Decision
2020-04-28 09:55
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-04-28 23:43
Articles in Press
2020-04-28 23:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-05-13 01:26
Publish the Manuscript Online
2020-05-14 03:43
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Genetic association analysis of CLEC5A and CLEC7A gene single-nucleotide polymorphisms and Crohn’s disease
Manuscript Source Unsolicited Manuscript
All Author List Nagi Elleisy, Sarah Rohde, Astrid Huth, Nicole Gittel, Änne Glass, Steffen Möller, Georg Lamprecht, Holger Schäffler and Robert Jaster
ORCID
Author(s) ORCID Number
Nagi Elleisy http://orcid.org/0000-0002-0200-2873
Sarah Rohde http://orcid.org/0000-0002-6892-1565
Astrid Huth http://orcid.org/0000-0002-0858-7948
Nicole Gittel http://orcid.org/0000-0002-7134-069X
Änne Glass http://orcid.org/0000-0002-7715-9058
Steffen Möller http://orcid.org/0000-0002-7187-4683
Georg Lamprecht http://orcid.org/0000-0003-0997-3135
Holger Schäffler http://orcid.org/0000-0002-8475-3741
Robert Jaster http://orcid.org/0000-0002-8220-4570
Funding Agency and Grant Number
Funding Agency Grant Number
Damp-Foundation 2016-04
Corresponding Author Robert Jaster, MD, Academic Research, Professor, Senior Postdoctoral Fellow, Senior Scientist, Department of Medicine II, Division of Gastroenterology, Rostock University Medical Center, E.-Heydemann-Str. 6, Rostock 18057, Germany. robert.jaster@med.uni-rostock.de
Key Words Crohn’s disease; Single nucleotide polymorphisms; NOD2; CLEC5A; Gene expression; CXCL5
Core Tip The genetic traits of Crohn’s disease (CD) are incompletely understood. Here, we report a potential association of single nucleotide polymorphism (SNP) rs1285933 in CLEC5A, a member of the C-type lectin domain family of pattern recognition receptors, with CD. Variants of SNP rs1285933 had no impact on CLEC5A gene expression in peripheral blood mononuclear cells but correlated with the expression of CXCL5. The SNPs rs2078178 and rs16910631 in CLEC7A were not associated with the disease. The role of CLEC5A in the pathophysiology of CD deserves further attention.
Publish Date 2020-05-14 03:43
Citation Elleisy N, Rohde S, Huth A, Gittel N, Glass Ä, Möller S, Lamprecht G, Schäffler H, Jaster R. Genetic association analysis of CLEC5A and CLEC7A gene single-nucleotide polymorphisms and Crohn’s disease. World J Gastroenterol 2020; 26(18): 2194-2202
URL https://www.wjgnet.com/1007-9327/full/v26/i18/2194.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i18.2194
Full Article (PDF) WJG-26-2194.pdf
Full Article (Word) WJG-26-2194.docx
Manuscript File 54433-Review.docx
Answering Reviewers 54433-Answering reviewers.pdf
Audio Core Tip 54433-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 54433-Conflict-of-interest statement.pdf
Copyright License Agreement 54433-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 54433-Grant application form(s).pdf
Institutional Review Board Approval Form or Document 54433-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 54433-Language certificate.pdf
Peer-review Report 54433-Peer-review(s).pdf
Scientific Misconduct Check 54433-Bing-Tang JZ-2.png
Scientific Misconduct Check 54433-Scientific misconduct check.pdf
Scientific Editor Work List 54433-Scientific editor work list.pdf