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9/22/2020 6:23:06 AM | Browse: 176 | Download: 259
Publication Name World Journal of Stem Cells
Manuscript ID 55615
Country/Territory China
2020-03-25 20:52
Peer-Review Started
2020-03-25 20:56
To Make the First Decision
Return for Revision
2020-04-29 21:53
2020-05-25 11:03
Second Decision
2020-06-02 08:32
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-06-02 18:24
Articles in Press
2020-06-02 18:24
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-06-11 01:15
Typeset the Manuscript
2020-08-23 13:04
Publish the Manuscript Online
2020-09-22 06:23
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Orthopedics
Manuscript Type Review
Article Title Mechanisms of action of neuropeptide Y on stem cells and its potential applications in orthopaedic disorders
Manuscript Source Invited Manuscript
All Author List Jian-Qun Wu, Nan Jiang and Bin Yu
Author(s) ORCID Number
Jian-Qun Wu http://orcid.org/0000-0002-6805-7746
Nan Jiang http://orcid.org/0000-0003-2416-1653
Bin Yu http://orcid.org/0000-0002-3109-2062
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81830079
Guangzhou Health Science and Technology Project 20191A011116
Science and Technology Project of Guangzhou Huadu District 18-HDWS-003
Corresponding Author Bin Yu, MD, PhD, Professor, Surgeon, Department of Orthopedics, Nanfang Hospital, Southern Medical University, No. 1838, Guangzhou Ave. North, Baiyun District, Guangzhou 510515, Guangdong Province, China. smuyubin@163.com
Key Words Neuropeptide Y; Bone marrow mesenchymal stem cells; Hematopoietic stem cells; Fracture; Osteoporosis; Osteoarthritis
Core Tip Neuropeptide Y (NPY) system is crucial for bone metabolism and homeostasis. NPY can regulate biological effects of different types of cells through central and peripheral nervous systems. Here, we summarized recent findings regarding the roles of NPY and its receptors in bone metabolism and homeostasis, discussed biological actions and underlying mechanisms of NPY on bone marrow mesenchymal stem cells, hematopoietic stem cells, endothelial cells and chondrocytes. We also reviewed potential applications and efficacy of NPY and NPY receptor-targeted drugs in the treatment of fracture healing, osteoporosis and osteoarthritis.
Publish Date 2020-09-22 06:23
Citation Wu JQ, Jiang N, Yu B. Mechanisms of action of neuropeptide Y on stem cells and its potential applications in orthopaedic disorders. World J Stem Cells 2020; 12(9): 986-1000
URL https://www.wjgnet.com/1948-0210/full/v12/i9/986.htm
DOI https://dx.doi.org/10.4252/wjsc.v12.i9.986
Full Article (PDF) WJSC-12-986.pdf
Full Article (Word) WJSC-12-986.docx
Manuscript File 55615-Review_WangTQ.docx
Answering Reviewers 55615-Answering reviewers.pdf
Audio Core Tip 55615-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 55615-Conflict-of-interest statement.pdf
Copyright License Agreement 55615-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 55615-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 55615-Language certificate.pdf
Peer-review Report 55615-Peer-review(s).pdf
Scientific Misconduct Check 55615-Bing-Zhang H-1.png
Scientific Misconduct Check 55615-Bing-Yan JP-2.png
Scientific Misconduct Check 55615-Scientific misconduct check.pdf
Scientific Editor Work List 55615-Scientific editor work list.pdf