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9/4/2020 7:25:49 AM | Browse: 561 | Download: 1289
Publication Name World Journal of Gastroenterology
Manuscript ID 57087
Country China
Received
2020-05-29 17:02
Peer-Review Started
2020-05-29 17:03
To Make the First Decision
Return for Revision
2020-06-12 18:08
Revised
2020-06-14 13:14
Second Decision
2020-07-31 09:47
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-08-01 05:47
Articles in Press
2020-08-01 05:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-08-07 02:01
Typeset the Manuscript
2020-08-24 00:53
Publish the Manuscript Online
2020-09-04 07:25
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Liver fat accumulation measured by high-speed T2-corrected multi-echo magnetic resonance spectroscopy can predict risk of cholelithiasis
Manuscript Source Unsolicited Manuscript
All Author List Hong Chen, Wei-Ke Zeng, Guang-Zi Shi, Ming Gao, Meng-Zhu Wang and Jun Shen
ORCID
Author(s) ORCID Number
Hong Chen http://orcid.org/0000-0001-9057-3766
Wei-Ke Zeng http://orcid.org/0000-0002-9869-7023
Guang-Zi Shi http://orcid.org/0000-0003-0170-7895
Ming Gao http://orcid.org/0000-0003-4602-4393
Meng-Zhu Wang http://orcid.org/0000-0001-5674-4162
Jun Shen http://orcid.org/0000-0001-7746-5285
Funding Agency and Grant Number
Corresponding Author Jun Shen, MD, Doctor, Professor, Department of Radiology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, No. 107, Yanjiang Road West, Guangzhou 510120, Guangdong Province, China. shenjun@mail.sysu.edu.cn
Key Words Magnetic resonance spectroscopy; Cholelithiasis; Liver fat accumulation; Steatosis; Iron;
Core Tip The increase in total cholesterol synthesis can cause tissues to be overloaded with fatty acids, resulting in more lithogenic bile due to overproduction of hepatic cholesterol. Our study showed that patients with cholelithiasis had higher liver fat content and R2 value as assessed by high speed T2-corrected multi-echo magnetic resonance spectroscopy (MRS). MRS can be used for quantitative detection of mild liver steatosis, and proton density fat fraction (PDFF) derived from MRS can predict the risk of cholelithiasis. PDFF measured by MRS can quantitatively detect liver steatosis in a simple breath-hold of 15 s, which holds a good potential for clinical application.
Publish Date 2020-09-04 07:25
Citation Chen H, Zeng WK, Shi GZ, Gao M, Wang MZ, Shen J. Liver fat accumulation measured by high-speed T2-corrected multi-echo magnetic resonance spectroscopy can predict risk of cholelithiasis. World J Gastroenterol 2020; 26(33): 4996-5007
URL https://www.wjgnet.com/1007-9327/full/v26/i33/4996.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i33.4996
Full Article (PDF) WJG-26-4996.pdf
Full Article (Word) WJG-26-4996.docx
Manuscript File 57087-Review_WangTQ.docx
Answering Reviewers 57087-Answering reviewers.pdf
Audio Core Tip 57087-Audio core tip.m4a
Biostatistics Review Certificate 57087-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 57087-Conflict-of-interest statement.pdf
Copyright License Agreement 57087-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 57087-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 57087-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 57087-Language certificate.pdf
Peer-review Report 57087-Peer-review(s).pdf
Scientific Misconduct Check 57087-Bing-Yan JP-1.png
Scientific Misconduct Check 57087-Bing-Yan JP-2.png
Scientific Misconduct Check 57087-Scientific misconduct check.pdf
Scientific Editor Work List 57087-Scientific editor work list.pdf