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5/20/2021 3:14:20 PM | Browse: 493 | Download: 1426
Publication Name World Journal of Hepatology
Manuscript ID 62721
Country/Territory Russia
Received
2021-01-16 19:14
Peer-Review Started
2021-01-16 19:16
To Make the First Decision
Return for Revision
2021-02-24 23:25
Revised
2021-02-28 11:56
Second Decision
2021-04-20 13:23
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-04-22 14:19
Articles in Press
2021-04-22 14:19
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2021-04-27 15:52
Publish the Manuscript Online
2021-05-20 15:14
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Case Control Study
Article Title Gut dysbiosis is associated with poorer long-term prognosis in cirrhosis
Manuscript Source Invited Manuscript
All Author List Roman Maslennikov, Vladimir Ivashkin, Irina Efremova, Aliya Alieva, Ekaterina Kashuh, Ekaterina Tsvetaeva, Elena Poluektova, Elena Shirokova and Konstantin Ivashkin
ORCID
Author(s) ORCID Number
Roman Maslennikov http://orcid.org/0000-0001-7513-1636
Vladimir Ivashkin http://orcid.org/0000-0002-6815-6015
Irina Efremova http://orcid.org/0000-0002-4112-0426
Aliya Alieva http://orcid.org/0000-0002-7606-2246
Ekaterina Kashuh http://orcid.org/0000-0002-1244-0201
Ekaterina Tsvetaeva http://orcid.org/0000-0002-1323-1751
Elena Poluektova http://orcid.org/0000-0002-9038-3732
Elena Shirokova http://orcid.org/0000-0002-6819-0889
Konstantin Ivashkin http://orcid.org/0000-0002-5699-541X
Funding Agency and Grant Number
Funding Agency Grant Number
Biocodex Microbiota Foundation - National Research Grant Russia 2019
Corresponding Author Roman Maslennikov, MD, PhD, Professor, Department of Internal Medicine, Gastroenterology and Hepatology, Sechenov University, Pogodinskaya Street, 1, bld. 1, Moscow 119435, Russia. mmmm00@yandex.ru
Key Words Cirrhosis; Dysbiosis; Gut; ROC-analysis; Microbiota; Microbiome; Gut-liver axis
Core Tip The mortality rate of patients with severe dysbiosis was significantly higher than that of patients with non-severe dysbiosis. The abundance of enterobacteriaceae, proteobacteria, and lactobacillaceae was increased and the abundance of firmicutes and clostridia was decreased in the deceased patients compared with survivors. The abundance of bacilli, enterococcaceae and lactobacillaceae was higher and the abundance of clostridia was lower in those who died during the first year of follow-up compared with those who survived this year. The abundance of enterobacteriaceae and proteobacteria was higher in those who died in 2nd-4th years of follow-up compared with survivors.
Publish Date 2021-05-20 15:14
Citation Maslennikov R, Ivashkin V, Efremova I, Alieva A, Kashuh E, Tsvetaeva E, Poluektova E, Shirokova E, Ivashkin K. Gut dysbiosis is associated with poorer long-term prognosis in cirrhosis. World J Hepatol 2021; 13(5): 557-570
URL https://www.wjgnet.com/1948-5182/full/v13/i5/557.htm
DOI https://dx.doi.org/10.4254/wjh.v13.i5.557
Full Article (PDF) WJH-13-557.pdf
Full Article (Word) WJH-13-557.docx
Manuscript File 62721_Auto_Edited_LM.docx
Answering Reviewers 62721-Answering reviewers.pdf
Audio Core Tip 62721-Audio core tip.mp3
Biostatistics Review Certificate 62721-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 62721-Conflict-of-interest statement.pdf
Copyright License Agreement 62721-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 62721-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 62721-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 62721-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 62721-Language certificate.pdf
Peer-review Report 62721-Peer-review(s).pdf
Scientific Misconduct Check 62721-Bing-Wang JL-1.jpg
Scientific Misconduct Check 62721-Scientific misconduct check.pdf
Scientific Editor Work List 62721-Scientific editor work list.pdf