Publication Name	World Journal of Orthopedics
Manuscript ID	64688
Country	Japan

Received	2021-03-08 09:33
Peer-Review Started	2021-03-08 09:36
To Make the First Decision
Return for Revision	2021-03-31 00:45
Revised	2021-04-12 12:49
Second Decision	2021-08-04 03:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-08-04 08:04
Articles in Press	2021-08-04 08:04
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-09-05 14:58
Publish the Manuscript Online	2021-09-14 09:36

ISSN	2218-5836 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Orthopedics
Manuscript Type	Minireviews
Article Title	Effects of sclerostin antibody on bone healing
Manuscript Source	Invited Manuscript
All Author List	Atsushi Mihara, Kiminori Yukata, Toshihiro Seki, Ryuta Iwanaga, Norihiro Nishida, Kenzo Fujii, Yuji Nagao and Takashi Sakai
ORCID	Author(s) ORCID Number Atsushi Mihara http://orcid.org/0000-0002-5777-0204 Kiminori Yukata http://orcid.org/0000-0002-0040-1352 Toshihiro Seki http://orcid.org/0000-0002-5313-864X Ryuta Iwanaga http://orcid.org/0000-0001-8564-606X Norihiro Nishida http://orcid.org/0000-0001-7754-6579 Kenzo Fujii http://orcid.org/0000-0002-0028-4221 Yuji Nagao http://orcid.org/0000-0002-1701-6960 Takashi Sakai http://orcid.org/0000-0001-6367-1299
Funding Agency and Grant Number
Corresponding Author	Kiminori Yukata, MD, PhD, Associate Professor, Department of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube 755-8505, Japan. kyukata2004jp@yahoo.co.jp
Key Words	Canonical Wnt-β-catenin pathway; Fracture healing; Osteoporosis; Romosozumab; Sclerostin antibody
Core Tip	Sclerostin antibody (Scl-Ab) has been recently introduced for the treatment of osteoporosis. Several researchers have reported on the effects of Scl-Ab in bone fracture healing because of its rich osteogenic potential. In this review, we describe the latest reports of preclinical and clinical studies on the bone-healing effects of Scl-Ab.
Publish Date	2021-09-14 09:36
Citation	Mihara A, Yukata K, Seki T, Iwanaga R, Nishida N, Fujii K, Nagao Y, Sakai T. Effects of sclerostin antibody on bone healing. World J Orthop 2021; 12(9): 651-659
URL	https://www.wjgnet.com/2218-5836/full/v12/i9/651.htm
DOI	https://dx.doi.org/10.5312/wjo.v12.i9.651

Full Article (PDF)	WJO-12-651.pdf
Full Article (Word)	WJO-12-651.docx
Manuscript File	64688_Auto_Edited-JPY.docx
Answering Reviewers	64688-Answering reviewers.pdf
Audio Core Tip	64688-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	64688-Conflict-of-interest statement.pdf
Copyright License Agreement	64688-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	64688-Language certificate.pdf
Peer-review Report	64688-Peer-review(s).pdf
Scientific Misconduct Check	64688-Scientific misconduct check.pdf
Scientific Editor Work List	64688-Scientific editor work list.pdf
CrossCheck Report	64688-CrossCheck report.pdf