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Articles Published Processes
6/12/2021 10:20:44 PM | Browse: 603 | Download: 825
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Received |
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2021-02-28 12:11 |
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Peer-Review Started |
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2021-02-28 12:19 |
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To Make the First Decision |
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Return for Revision |
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2021-05-05 18:48 |
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Revised |
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2021-05-13 15:35 |
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Second Decision |
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2021-06-03 08:32 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2021-06-03 12:04 |
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Articles in Press |
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2021-06-03 12:04 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-06-09 12:35 |
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Publish the Manuscript Online |
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2021-06-12 22:20 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Pediatric metabolic liver diseases: Evolving role of liver transplantation
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jagadeesh Menon, Mukul vij, Deepti Sachan, Ashwin Rammohan, Naresh Shanmugam, Ilankumaran Kaliamoorthy and Mohamed Rela |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Mukul vij, MD, Doctor, Department of Pathology, Dr Rela Institute and Medical Center, Chromepet, Chennai 600044, Tamil Nadu, India. mukul.vij.path@gmail.com |
| Key Words |
Liver transplantation; Metabolic liver disease; Tyrosinemia; Wilson disease; Glycogen storage diseases; Urea cycle disorders; Pathology; Auxiliary liver transplant |
| Core Tip |
Metabolic disorders are important cause of morbidity and mortality in children. Their clinical presentations are varied and include end-stage liver disease, hepatocellular cancer, renal tubular acidosis, seizures, encephalopathy, myopathy etc. Liver transplantation (LT) is a curative option in many metabolic disorders. LT is contraindicated in mitochondrial disorders with significant extrahepatic involvement. A combined liver kidney transplant is needed in disorders where the underlying defects significantly damages both the organs. The outcome of LT is excellent in metabolic disorders. Auxiliary partial orthotopic LT is an attractive option as it provides the defective enzymes keeping the native liver intact and may hold an option of withdrawing immunosuppression in case gene therapy can be offered in future. |
| Publish Date |
2021-06-12 22:20 |
| Citation |
Menon J, vij M, Sachan D, Rammohan A, Shanmugam N, Kaliamoorthy I, Rela M. Pediatric metabolic liver diseases: Evolving role of liver transplantation. World J Transplant 2021; 11(6): 161-179 |
| URL |
https://www.wjgnet.com/2220-3230/full/v11/i6/161.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v11.i6.161 |
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