Publication Name	World Journal of Hepatology
Manuscript ID	65554
Country	Egypt

Received	2021-03-09 19:22
Peer-Review Started	2021-03-09 19:32
To Make the First Decision
Return for Revision	2021-05-02 05:31
Revised	2021-05-20 01:58
Second Decision	2021-10-21 06:25
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-10-25 02:00
Articles in Press	2021-10-25 02:00
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-12-16 11:07
Publish the Manuscript Online	2021-12-27 05:24

ISSN	1948-5182 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Retrospective Study
Article Title	Biliary complications in recipients of living donor liver transplantation: A single-centre study
Manuscript Source	Invited Manuscript
All Author List	Reginia Nabil Guirguis, Ehab Hasan Nashaat, Azza Emam Yassin, Wesam Ahmed Ibrahim, Shereen A Saleh, Mohamed Bahaa, Mahmoud El-Meteini, Mohamed Fathy, Hany Mansour Dabbous, Iman Fawzy Montasser, Manar Salah and Ghada Abdelrahman Mohamed
ORCID	Author(s) ORCID Number Reginia Nabil Guirguis http://orcid.org/0000-0003-3442-3629 Ehab Hasan Nashaat http://orcid.org/0000-0002-7686-6463 Azza Emam Yassin http://orcid.org/0000-0002-5764-6078 Wesam Ahmed Ibrahim http://orcid.org/0000-0003-1813-5248 Shereen A Saleh http://orcid.org/0000-0002-0984-1725 Mohamed Bahaa http://orcid.org/0000-0002-8605-4397 Mahmoud El-Meteini http://orcid.org/0000-0002-1839-3549 Mohamed Fathy http://orcid.org/0000-0001-8000-5722 Hany Mansour Dabbous http://orcid.org/0000-0001-5648-7733 Iman Fawzy Montasser http://orcid.org/0000-0002-1351-978X Manar Salah http://orcid.org/0000-0001-9909-4016 Ghada Abdelrahman Mohamed http://orcid.org/0000-0003-0320-1011
Funding Agency and Grant Number
Corresponding Author	Ghada Abdelrahman Mohamed, MD, Lecturer, Gastroenterology and Hepatology Unit, Department of Internal Medicine, Faculty of Medicine, Ain Shams University, El-Khalifa El-Maamon St., Abbassia, Cairo 11591, Egypt. ghadaabdelrahman@med.asu.edu.eg
Key Words	Biliary complications; Living donor liver transplantation; Retrospective analysis; Bile leak; Biliary stricture; Risk factors; Mortality; Graft rejection
Core Tip	We included 169 right lobe living-donor liver transplantation recipients in this retrospective study. The overall incidence rate of biliary complications including biliary leakage, biliary infection and biliary stricture was 57.4%. Twenty-seven (16%) patients experienced chronic graft rejection. Graft failure developed in 20 (11.8%) patients. A total of 28 (16.6%) deaths occurred during follow-up. Biliary complications were an independent risk factor for the occurrence of chronic graft rejection and failure; however, mortality was determined by unresolved recurrent hepatitis C virus infection. In conclusion, biliary complications represent an independent risk factor for chronic graft rejection and graft failure; nonetheless, effective management of these complications can improve patient and graft survival.
Publish Date	2021-12-27 05:24
Citation	Guirguis RN, Nashaat EH, Yassin AE, Ibrahim WA, Saleh SA, Bahaa M, El-Meteini M, Fathy M, Dabbous HM, Montasser IF, Salah M, Mohamed GA. Biliary complications in recipients of living donor liver transplantation: A single-centre study. World J Hepatol 2021; 13(12): 2081-2103
URL	https://www.wjgnet.com/1948-5182/full/v13/i12/2081.htm
DOI	https://dx.doi.org/10.4254/wjh.v13.i12.2081

Full Article (PDF)	WJH-13-2081.pdf
Full Article (Word)	WJH-13-2081.docx
Manuscript File	65554_Auto_Edited.docx
Answering Reviewers	65554-Answering reviewers.pdf
Audio Core Tip	65554-Audio core tip.mp3
Biostatistics Review Certificate	65554-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	65554-Conflict-of-interest statement.pdf
Copyright License Agreement	65554-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	65554-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	65554-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	65554-Language certificate.pdf
Supplementary Material	65554-Supplementary material.pdf
Peer-review Report	65554-Peer-review(s).pdf
Scientific Misconduct Check	65554-Bing-Wu YXJ-2.png
Scientific Editor Work List	65554-Scientific editor work list.pdf
CrossCheck Report	65554-CrossCheck report.pdf