| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Biliary complications in recipients of living donor liver transplantation: A single-centre study
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Reginia Nabil Guirguis, Ehab Hasan Nashaat, Azza Emam Yassin, Wesam Ahmed Ibrahim, Shereen A Saleh, Mohamed Bahaa, Mahmoud El-Meteini, Mohamed Fathy, Hany Mansour Dabbous, Iman Fawzy Montasser, Manar Salah and Ghada Abdelrahman Mohamed |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ghada Abdelrahman Mohamed, MD, Lecturer, Gastroenterology and Hepatology Unit, Department of Internal Medicine, Faculty of Medicine, Ain Shams University, El-Khalifa El-Maamon St., Abbassia, Cairo 11591, Egypt. ghadaabdelrahman@med.asu.edu.eg |
| Key Words |
Biliary complications; Living donor liver transplantation; Retrospective analysis; Bile leak; Biliary stricture; Risk factors; Mortality; Graft rejection |
| Core Tip |
We included 169 right lobe living-donor liver transplantation recipients in this retrospective study. The overall incidence rate of biliary complications including biliary leakage, biliary infection and biliary stricture was 57.4%. Twenty-seven (16%) patients experienced chronic graft rejection. Graft failure developed in 20 (11.8%) patients. A total of 28 (16.6%) deaths occurred during follow-up. Biliary complications were an independent risk factor for the occurrence of chronic graft rejection and failure; however, mortality was determined by unresolved recurrent hepatitis C virus infection. In conclusion, biliary complications represent an independent risk factor for chronic graft rejection and graft failure; nonetheless, effective management of these complications can improve patient and graft survival. |
| Publish Date |
2021-12-27 05:24 |
| Citation |
Guirguis RN, Nashaat EH, Yassin AE, Ibrahim WA, Saleh SA, Bahaa M, El-Meteini M, Fathy M, Dabbous HM, Montasser IF, Salah M, Mohamed GA. Biliary complications in recipients of living donor liver transplantation: A single-centre study. World J Hepatol 2021; 13(12): 2081-2103 |
| URL |
https://www.wjgnet.com/1948-5182/full/v13/i12/2081.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v13.i12.2081 |
