Publication Name	World Journal of Clinical Cases
Manuscript ID	88949
Country	China

Received	2023-10-16 11:14
Peer-Review Started	2023-10-16 11:16
To Make the First Decision
Return for Revision	2023-11-28 01:21
Revised	2023-12-12 16:24
Second Decision	2024-01-16 02:46
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2024-01-16 07:57
Articles in Press	2024-01-16 07:57
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-01-25 05:56
Publish the Manuscript Online	2024-01-31 06:42

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Clinical and Translational Research
Article Title	Causal associations between gastroesophageal reflux disease and essential hypertension: A bidirectional Mendelian randomization study
Manuscript Source	Unsolicited Manuscript
All Author List	Ning Wei, Ming-Hui Liu and Yu-Hu Song
ORCID	Author(s) ORCID Number Ning Wei http://orcid.org/0000-0001-8931-8995 Yu-Hu Song http://orcid.org/0000-0003- 4178-4916
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China (General Program) 82070631
Corresponding Author	Yu-Hu Song, MD, PhD, Professor, Division of Gastroenterology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No. 1277 Jiefang Avenue, Wuhan 430022, Hubei Province, China. yuhusong@163.com
Key Words	Gastroesophageal reflux disease; Essential hypertension; Hypertensive heart disease; Mendelian randomization study
Core Tip	This study used a method of bidirectional Mendelian randomization, and its results highlighted that gastroesophageal reflux disease (GERD) was positively associated with the risk of essential hypertension, suggesting a new prevent strategy and therapeutic perspectives of essential hypertension in patients with GERD.
Publish Date	2024-01-31 06:42
Citation	Wei N, Liu MH, Song YH. Causal associations between gastroesophageal reflux disease and essential hypertension: A bidirectional Mendelian randomization study. World J Clin Cases 2024; 12(5): 880-890
URL	https://www.wjgnet.com/2307-8960/full/v12/i5/880.htm
DOI	https://dx.doi.org/10.12998/wjcc.v12.i5.880

Full Article (PDF)	WJCC-12-880-with-cover.pdf
Full Article (Word)	WJCC-12-880.docx
Manuscript File	88949_Auto_Edited-YJP.docx
Answering Reviewers	88949-Answering reviewers.pdf
Audio Core Tip	88949-Audio core tip.mp3
Biostatistics Review Certificate	88949-Biostatistics statement.pdf
Clinical Trial Registration Statement	88949-Clinical trial registration statement.pdf
Conflict-of-Interest Disclosure Form	88949-Conflict-of-interest statement.pdf
Copyright License Agreement	88949-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	88949-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s)	88949-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	88949-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate	88949-Language certificate.pdf
Supplementary Material	88949-Supplementary material.pdf
Peer-review Report	88949-Peer-review(s).pdf
Scientific Misconduct Check	88949-Bing-Qu XL-2.png
Scientific Editor Work List	88949-Scientific editor work list.pdf