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Articles Published Processes
8/7/2020 11:36:53 AM | Browse: 660 | Download: 1594
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Received |
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2020-04-11 14:12 |
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Peer-Review Started |
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2020-04-11 14:12 |
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To Make the First Decision |
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Return for Revision |
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2020-05-21 21:44 |
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Revised |
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2020-07-04 07:48 |
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Second Decision |
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2020-07-14 11:49 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2020-07-14 23:28 |
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Articles in Press |
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2020-07-14 23:28 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-07-20 00:20 |
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Typeset the Manuscript |
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2020-08-04 07:28 |
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Publish the Manuscript Online |
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2020-08-07 11:36 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical and Translational Research |
| Article Title |
Role of nutritional status and nutritional support in outcome of hepatitis B virus-associated acute-on-chronic liver failure
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Yue Chang, Qin-Yu Liu, Qing Zhang, Ya-Mei Rong, Cheng-Zhen Lu and Hai Li |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Tianjin Science and Technology Project |
15ZXLCSY00040 |
| National Major Science and Technology Projects in the 13th Five-Year Plan |
2018ZX10732-202-004-005 |
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| Corresponding Author |
Hai Li, MD, Professor, Division of Gastroenterology and Hepatology, Tianjin Xiqing Hospital, No. 403, Xiqing Road, Xiqing District, Tianjin 300380, China. haili_tj@sina.com |
| Key Words |
Liver failure; Hepatitis B; Nutrition therapy; Intestinal host defense; Cytokine; Prognosis |
| Core Tip |
In this study, we investigate the nutritional risk, nutritional status, and the biomarkers of the gastrointestinal barrier in patients with hepatitis B virus-associated acute-on-chronic liver failure (HBV-ACLF). We found poor nutritional intake and high nutritional risk, with some markers of impaired gastrointestinal barrier function in HBV-ACLF patients. Blood cytokines, endotoxin, and D-lactate seemed potential predictors of death. Individualized and dynamic nutritional support was associated with a better prognosis of 28-day mortality. Moreover, nutritional support can also improve the gastrointestinal barrier function in survivors. Thus, nutritional status is not only the prognostic factor but also the therapeutic target in HBV-ACLF. |
| Publish Date |
2020-08-07 11:36 |
| Citation |
Chang Y, Liu QY, Zhang Q, Rong YM, Lu CZ, Li H. Role of nutritional status and nutritional support in outcome of hepatitis B virus-associated acute-on-chronic liver failure. World J Gastroenterol 2020; 26(29): 4288-4301 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i29/4288.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i29.4288 |
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