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1/21/2019 5:38:30 AM | Browse: 735 | Download: 1318
Publication Name World Journal of Gastroenterology
Manuscript ID 43250
Country China
Received
2018-10-30 01:11
Peer-Review Started
2018-10-30 02:50
To Make the First Decision
2018-11-15 03:41
Return for Revision
2018-11-15 06:06
Revised
2018-12-12 07:28
Second Decision
2018-12-21 09:30
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2018-12-21 22:03
Articles in Press
2018-12-21 22:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-01-01 12:43
Typeset the Manuscript
2019-01-17 07:10
Publish the Manuscript Online
2019-01-21 05:38
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Effects of positive acceleration (+Gz stress) on liver enzymes, energy metabolism, and liver histology in rats
Manuscript Source Unsolicited Manuscript
All Author List Bin Shi, Xian-Qiang Wang, Wei-Dong Duan, Guo-Dong Tan, Han-Jing Gao, Ying-Wei Pan, Qing-Jun Guo and Hong-Yi Zhang
ORCID
Author(s) ORCID Number
Bin Shi http://orcid.org/0000-0002-1524-1574
Xian-Qiang Wang http://orcid.org/0000-0002-3279-8411
Wei-Dong Duan http://orcid.org/0000-0002-9405-6720
Guo-Dong Tan http://orcid.org/0000-0001-9558-9994
Han-Jing Gao http://orcid.org/0000-0002-9460-2525
Ying-Wei Pan http://orcid.org/0000-0002-5852-8727
Qing-Jun Guo http://orcid.org/0000-0002-9108-489X
Hong-Yi Zhang http://orcid.org/0000-0002-7521-5247
Funding Agency and Grant Number
Funding Agency Grant Number
the China Post-doctoral Science Foundation Project 2018T111151
Corresponding Author Hong-Yi Zhang, MD, Full Professor, Department of Hepatobiliary Surgery, Chinese PLA Air Force General Hospital, No.30 Fucheng Road, Haidian District, Beijing 100142, China. qhcgzhy@163.com
Key Words Positive acceleration; +Gz; Liver function; Animal models; Liver metabolism; Ischemia-reperfusion injury
Core Tip Some clinical data showed that liver dysfunction was observed in pilots. However, the reason was not clear. We conducted this experimental study to investigate rat liver function changes in response to repeated +Gz exposures, and to observe the portal venous flow volume, liver function indexes, liver tissue malondialdehyde, Na+-K+-ATPase activity, and changes in liver histology. We found that repeated +Gz exposures transiently cause hepatocyte injury and affect liver metabolism and morphological structure.
Publish Date 2019-01-21 05:38
Citation Shi B, Wang XQ, Duan WD, Tan GD, Gao HJ, Pan YW, Guo QJ, Zhang HY. Effects of positive acceleration (+Gz stress) on liver enzymes, energy metabolism, and liver histology in rats. World J Gastroenterol 2019; 25(3): 346-355
URL https://www.wjgnet.com/1007-9327/full/v25/i3/346.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i3.346
Full Article (PDF) WJG-25-346.pdf
Full Article (Word) WJG-25-346.docx
The ARRIVE Guidelines 43250-The ARRIVE guidelines.pdf
Manuscript File 43250-Review.doc
Answering Reviewers 43250-Answering reviewers.pdf
Audio Core Tip 43250-Audio core tip.mp3
Biostatistics Review Certificate 43250-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 43250-Conflict-of-interest statement.pdf
Copyright License Agreement 43250-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 43250-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 43250-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 43250-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 43250-Language certificate.pdf
Supplementary Material 43250-Supplementary-Material-revision.rar
Peer-review Report 43250-Peer-review(s).pdf
Scientific Misconduct Check 43250-Scientific misconduct check.pdf
Scientific Editor Work List 43250-Scientific editor work list.pdf