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7/23/2020 5:00:01 AM | Browse: 829 | Download: 1388
Publication Name World Journal of Hepatology
Manuscript ID 54693
Country/Territory Thailand
Received
2020-02-13 08:51
Peer-Review Started
2020-02-13 08:51
To Make the First Decision
Return for Revision
2020-04-29 21:17
Revised
2020-05-12 11:34
Second Decision
2020-05-29 06:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-05-30 22:14
Articles in Press
2020-05-30 22:14
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-06-10 06:00
Typeset the Manuscript
2020-07-10 08:55
Publish the Manuscript Online
2020-07-23 05:00
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Anti-inflammatory and anti-oxidant effects of aloe vera in rats with non-alcoholic steatohepatitis
Manuscript Source Unsolicited Manuscript
All Author List Naruemon Klaikeaw, Jutamas Wongphoom, Duangporn Werawatganon, Maneerat Chayanupatkul and Prasong Siriviriyakul
ORCID
Author(s) ORCID Number
Naruemon Klaikeaw http://orcid.org/0000-0001-8847-9692
Jutamas Wongphoom http://orcid.org/0000-0001-8847-9691
Duangporn Werawatganon http://orcid.org/0000-0001-8847-9690
Maneerat Chayanupatkul http://orcid.org/0000-0002-1649-5373
Prasong Siriviriyakul http://orcid.org/0000-0001-8847-9693
Funding Agency and Grant Number
Funding Agency Grant Number
Grant of Ratchadaphiseksomphot, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand RA59/035
Corresponding Author Duangporn Werawatganon, MD, MSc, Professor, Alternative and Complementary Medicine for Gastrointestinal and Liver Diseases Research Unit, Department of Physiology, Faculty of Medicine, Chulalongkorn University, Henri Dunant Road, Pathumwan, Bangkok 10330, Thailand. dr.duangporn@gmail.com
Key Words Non-alcoholic steatohepatitis; Aloe vera; Oxidative stress; Hepatic inflammation; Hepatocyte apoptosis; Peroxisome proliferators-activated receptor
Core Tip To the best of our knowledge, this is the first study to evaluate the therapeutic effects of aloe vera in non-alcoholic steatohepatitis (NASH). In this animal model of NASH, we found that aloe vera could decrease oxidative stress markers, replenish natural antioxidants, and reduce hepatic inflammation and hepatocyte apoptosis. Aloe vera could, in sum, alleviate the pathologic changes seen in NASH.
Publish Date 2020-07-23 05:00
Citation Klaikeaw N, Wongphoom J, Werawatganon D, Chayanupatkul M, Siriviriyakul P. Anti-inflammatory and anti-oxidant effects of aloe vera in rats with non-alcoholic steatohepatitis. World J Hepatol 2020; 12(7): 363-377
URL https://www.wjgnet.com/1948-5182/full/v12/i7/363.htm
DOI https://dx.doi.org/10.4254/wjh.v12.i7.363
Full Article (PDF) WJH-12-363.pdf
Full Article (Word) WJH-12-363.docx
The ARRIVE Guidelines 54693-The-ARRIVE-Guidelines-revision.pdf
Manuscript File 54693-Review-Webster J.docx
Answering Reviewers 54693-Answering reviewers.pdf
Audio Core Tip 54693-Audio core tip.mp3
Biostatistics Review Certificate 54693-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 54693-Conflict-of-interest statement.pdf
Copyright License Agreement 54693-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 54693-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 54693-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 54693-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 54693-Language certificate.pdf
Peer-review Report 54693-Peer-review(s).pdf
Scientific Misconduct Check 54693-Bing-Yan JP-2.png
Scientific Misconduct Check 54693-Scientific misconduct check.pdf
Scientific Editor Work List 54693-Scientific editor work list.pdf