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Articles Published Processes
3/16/2018 12:27:25 PM | Browse: 984 | Download: 1784
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Received |
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2018-01-11 09:13 |
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Peer-Review Started |
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2018-01-11 10:29 |
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To Make the First Decision |
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2018-02-24 01:23 |
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Return for Revision |
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2018-02-26 06:00 |
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Revised |
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2018-03-01 08:14 |
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Second Decision |
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2018-03-02 09:03 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2018-03-03 03:39 |
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Articles in Press |
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2018-03-03 03:39 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2018-03-15 09:31 |
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Publish the Manuscript Online |
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2018-03-16 12:27 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which selected by an in-house editor and fully peer-reviewed by external reviewers. It distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2018. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Low-FODMAP vs regular rye bread in irritable bowel syndrome: Randomized SmartPill® study
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Laura Pirkola, Reijo Laatikainen, Jussi Loponen, Sanna-Maria Hongisto, Markku Hillila, Anu Nuora, Baoru Yang, Kaisa M Linderborg and Riitta Freese |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Laura Pirkola, MSc, N/A, Research, Fazer Group/ Fazer Bakeries Ltd, Fazerintie 6, Vantaa FI-01230, Finland. laura.pirkola@fazer.com |
| Key Words |
Colonic pressure; FODMAP; Irritable bowel syndrome; Rye; Wireless motility capsule; Symptom severity |
| Core Tip |
Our study confirmed that low-FODMAP rye bread reduces colonic fermentation in irritable bowel syndrome (IBS) patients compared with regular rye bread. The observed correlation between increased intracolonic pressure and symptom severity underlines the central role of visceral sensitivity in IBS and suggests that some IBS symptoms might be exacerbated by any pathophysiological reason that leads to increased colonic pressure. The study also suggests that SmartPill might not be an optimal device to evaluate gastrointestinal circumstances during meal studies lasting less than 24 h, due to device’s inability to measure effects of a singular food bolus in a timely manner. |
| Publish Date |
2018-03-16 12:27 |
| Citation |
Pirkola L, Laatikainen R, Loponen J, Hongisto SM, Hillilä M, Nuora A, Yang B, Linderborg KM, Freese R. Low-FODMAP vs regular rye bread in irritable bowel syndrome: Randomized SmartPill® study. World J Gastroenterol 2018; 24(11): 1259-1268 |
| URL |
http://www.wjgnet.com/1007-9327/full/v24/i11/1259.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v24.i11.1259 |
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